A comparison of zero and first order Tikhonov regularization for an inhomogeneous volume

D. A. Lowther, R. D. Throne, L. G. Olson, J. R. Windle

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In this study we examine the effects of tissue inhomogeneities on epicardial estimates when using zero order Tikhonov and first order Tikhonov regularization. Epicardial potentials measured during an in-vivo swine experiment were projected to 96 body surface locations using an inhomogeneous transfer matrix constructed using a finite element model of the swine made from CT scans. It was assumed that the lungs, fat, and remaining volume had conductivities of 50, 40, and 220 μmho/mm. The inverse estimates were then computed from the body surface potentials where noise had been added to simulate measurement errors. The inverses were computed using the same inhomogeneous transfer matrix used for the the forward projection, and with a homogeneous transfer matrix.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology
Pages541-544
Number of pages4
StatePublished - 2001
EventComputer in Cardiology 2001 - Rotterdam, Netherlands
Duration: Sep 23 2001Sep 26 2001

Other

OtherComputer in Cardiology 2001
CountryNetherlands
CityRotterdam
Period9/23/019/26/01

ASJC Scopus subject areas

  • Software
  • Cardiology and Cardiovascular Medicine

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    Lowther, D. A., Throne, R. D., Olson, L. G., & Windle, J. R. (2001). A comparison of zero and first order Tikhonov regularization for an inhomogeneous volume. In Computers in Cardiology (pp. 541-544)