A comprehensive nomenclature for serine proteases with homology to tissue kallikreins

Åke Lundwall, Vimla Band, Michael Blaber, Judith A. Clements, Yves Courty, Eleftherios P. Diamandis, Hans Fritz, Hans Lilja, Johan Malm, Lois J. Maltais, A. Yvonne Olsson, Constantina Petraki, Andreas Scorilas, Georgia Sotiropoulou, Ulf Håkan Stenman, Carsten Stephan, Maroulio Talieri, George M. Yousef

Research output: Contribution to journalArticle

124 Scopus citations

Abstract

The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.

Original languageEnglish (US)
Pages (from-to)637-641
Number of pages5
JournalBiological Chemistry
Volume387
Issue number6
DOIs
StatePublished - Jun 1 2006

Keywords

  • Cancer
  • Evolution
  • Hormone
  • Inflammation
  • Kininogen

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Clinical Biochemistry

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    Lundwall, Å., Band, V., Blaber, M., Clements, J. A., Courty, Y., Diamandis, E. P., Fritz, H., Lilja, H., Malm, J., Maltais, L. J., Olsson, A. Y., Petraki, C., Scorilas, A., Sotiropoulou, G., Stenman, U. H., Stephan, C., Talieri, M., & Yousef, G. M. (2006). A comprehensive nomenclature for serine proteases with homology to tissue kallikreins. Biological Chemistry, 387(6), 637-641. https://doi.org/10.1515/BC.2006.082