Abstract
The human kallikrein locus on chromosome 19q13.3-13.4 contains kallikrein 1 - the tissue kallikrein - and 14 related serine proteases. Recent investigations into their function and evolution have indicated that the present nomenclature for these proteins is inadequate or insufficient. Here we present a new nomenclature in which proteins without proven kininogenase activity are denoted kallikrein-related peptidase. Names are also given to the unique rodent proteins that are closely related to kallikrein 1.
Original language | English (US) |
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Pages (from-to) | 637-641 |
Number of pages | 5 |
Journal | Biological Chemistry |
Volume | 387 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1 2006 |
Externally published | Yes |
Keywords
- Cancer
- Evolution
- Hormone
- Inflammation
- Kininogen
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology
- Clinical Biochemistry