A crosstalk-based linear filter in biochemical signal transduction pathways for the internet of bio-things

Massimiliano Laddomada, Massimiliano Pierobon

Research output: Chapter in Book/Report/Conference proceedingConference contribution

4 Scopus citations

Abstract

Novel emerging tools are allowing the manipulation and control of biological cells and their functions, e.g., sensing, actuation, and communication through biochemical stimuli. These tools have the potential to enable the implementation of manmade networks of biological computing devices, i.e., Internet of Bio-things. In this work, signal transduction pathways, i.e., cells' chemical reactions that process biochemical signals, are proposed for the design of analog linear filters to be utilized as components in the Internet of Bio-things. These filters, which exploit the crosstalk of signal transduction pathways to achieve the desired response, are here modeled and analyzed. The relations between filter properties and biochemical parameters are presented with the goal of designing a notch filter. A preliminary numerical example is also given as proof-of-concept.

Original languageEnglish (US)
Title of host publication2015 IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2015 - Proceedings
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages5520-5524
Number of pages5
ISBN (Electronic)9781467369978
DOIs
StatePublished - Aug 4 2015
Event40th IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2015 - Brisbane, Australia
Duration: Apr 19 2014Apr 24 2014

Publication series

NameICASSP, IEEE International Conference on Acoustics, Speech and Signal Processing - Proceedings
Volume2015-August
ISSN (Print)1520-6149

Other

Other40th IEEE International Conference on Acoustics, Speech, and Signal Processing, ICASSP 2015
CountryAustralia
CityBrisbane
Period4/19/144/24/14

Keywords

  • Biochemical filter design
  • crosstalk
  • internet of bio-things
  • molecular communication
  • signal transduction pathway

ASJC Scopus subject areas

  • Software
  • Signal Processing
  • Electrical and Electronic Engineering

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