A hg(ii)-mediated “signal-on” electrochemical glutathione sensor

Hamid R.Lotfi Zadeh Zhad, Rebecca Y. Lai

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


We report the design and fabrication of a DNA-based electrochemical sensor for detection of glutathione. Sensor signaling relies on glutathione's ability to chelate mercury Hg(II), displacing it from the thymine–Hg(II)–thymine complex formed between the surface-immobilized DNA probes. Our results show that this sensor is sensitive and selective enough to be employed in saliva.

Original languageEnglish (US)
Pages (from-to)8385-8387
Number of pages3
JournalChemical Communications
Issue number61
StatePublished - Jul 3 2014

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


Dive into the research topics of 'A hg(ii)-mediated “signal-on” electrochemical glutathione sensor'. Together they form a unique fingerprint.

Cite this