Abstract
A new pyrene-containing fluorescent sensor has been synthesized from 2,3,3-trimethylindolenine. Spectroscopic and photophysical properties of sensor are presented. The large change in fluorescence intensity (I/I0 = 0.13) at 381 nm and affinity to Hg2+ over other cations such as K+, Na+, Ca2+, Mg2+, Pb2+, and Cu2+ make this compound a useful chemosensor for Hg2+ detection in hydrophilic media. The sensor (6.0 × 10-6 M) displays significant fluorescence quenching upon addition of Hg2+ in pH 7.4 HEPES buffer without excimer formation. Job's plot analysis shows the binding stoichiometry to be 2:1 (host/guest).
Original language | English (US) |
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Pages (from-to) | 3422-3425 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 51 |
Issue number | 26 |
DOIs | |
State | Published - Jun 30 2010 |
Keywords
- Fluorescent sensor
- Hg
- Pyrene
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry