A hybrid giant cell granuloma and fibro-osseous lesion of the mandible

Kishore Shetty, Peter Giannini, Janet Leigh

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


We present a case of a 39-year-old African-American female who presents with a swelling of the left side of the face and jaw. A panoramic radiograph revealed a well-defined multilocular mixed lesion, which was predominantly radiolucent with scattered radiopacities within the left mandibular region along with thinning of the inferior cortex The histologic, radiographic, and clinical presentation are suggestive of a hybrid lesion with features of both central giant cell granuloma and cemento-osseous dysplasia. The patient was treated with complete surgical excision, curettage, and peripheral ostectomy. The post-operative course was uneventful. Hybrid lesions of the craniofacial bones comprised of both giant-cell and fibro-osseous components are uncommon, with only three such cases having been previously reported.

Original languageEnglish (US)
Pages (from-to)81-84
Number of pages4
JournalOral Oncology Extra
Issue number6-7
StatePublished - 2004
Externally publishedYes


  • Bone dysplasias
  • Giant cell granuloma
  • Mandible

ASJC Scopus subject areas

  • Oral Surgery
  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology


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