A lenslet-based device for measuring oxygen saturation in the retina

Jessica C. Ramella-Roman, H. Kandimalla, R. Dinga, A. Nabili, S. Mathews, Q. D. Nguyen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

Diabetic retinopathy (DR) is a complication of diabetes affecting up o 80% of all diabetic patients. DR can lead to blindness and reduced quality of life. Some authors have hypothesized that changes in the flow dynamics associated with DR as well as changes in retinal oxygenation can lead to macular edema. Measurements of oxygen saturation in the retina could help understand the real mechanisms behind this condition. We present a novel spectroscopic imaging device to measure oxygen saturation in the retina. Our system uses a lenslet array to spatially and spectrocopically divide a fundus image. A three wavelengths algorithm is used to calculate oxygen saturation in small vessels. Only wavelengths in the 500 - 580 nm range are considered in order to minimize the wavelength dependence of the scattering from erythrocytes. Preliminary testing on healthy subjects showed values of oxygen saturation comparable to the one reported in the literature.

Original languageEnglish (US)
Title of host publicationOphthalmic Technologies XVII
DOIs
StatePublished - Aug 31 2007
EventOphthalmic Technologies XVII - San Jose, CA, United States
Duration: Jan 20 2007Jan 23 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6426
ISSN (Print)1605-7422

Conference

ConferenceOphthalmic Technologies XVII
CountryUnited States
CitySan Jose, CA
Period1/20/071/23/07

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Keywords

  • Diabetic retinopathy
  • Lenslet
  • Oximetry

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Ramella-Roman, J. C., Kandimalla, H., Dinga, R., Nabili, A., Mathews, S., & Nguyen, Q. D. (2007). A lenslet-based device for measuring oxygen saturation in the retina. In Ophthalmic Technologies XVII [64261J] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 6426). https://doi.org/10.1117/12.714123