A long-wavelength xanthene dye for photoacoustic imaging

Xinqi Zhou; Yuan Fang; Viranga Wimalasiri; Cliff I. Stains; Evan W. Miller

doi:10.1039/d2cc03947h

A long-wavelength xanthene dye for photoacoustic imaging

Xinqi Zhou, Yuan Fang, Viranga Wimalasiri, Cliff I. Stains, Evan W. Miller

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Photoacoustic (PA) imaging is a powerful biomedical imaging modality. We designed KeTMR and KeJuR, two xanthene-based dyes that were readily obtained through a 2-step synthetic route. KeJuR has low molecular weight, good aqueous solubility, and superior chemical stability compared to KeTMR. KeJuR shows a robust PA signal under 860 nm excitation and can be paired with traditional PA dyes for multiplex imaging in blood samples under a tissue-mimicking environment.

Original language	English (US)
Pages (from-to)	11941-11944
Number of pages	4
Journal	Chemical Communications
Volume	58
Issue number	85
DOIs	https://doi.org/10.1039/d2cc03947h
State	Published - Oct 5 2022

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/d2cc03947h

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abstract = "Photoacoustic (PA) imaging is a powerful biomedical imaging modality. We designed KeTMR and KeJuR, two xanthene-based dyes that were readily obtained through a 2-step synthetic route. KeJuR has low molecular weight, good aqueous solubility, and superior chemical stability compared to KeTMR. KeJuR shows a robust PA signal under 860 nm excitation and can be paired with traditional PA dyes for multiplex imaging in blood samples under a tissue-mimicking environment.",

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AU - Zhou, Xinqi

AU - Fang, Yuan

AU - Wimalasiri, Viranga

AU - Stains, Cliff I.

AU - Miller, Evan W.

PY - 2022/10/5

Y1 - 2022/10/5

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AB - Photoacoustic (PA) imaging is a powerful biomedical imaging modality. We designed KeTMR and KeJuR, two xanthene-based dyes that were readily obtained through a 2-step synthetic route. KeJuR has low molecular weight, good aqueous solubility, and superior chemical stability compared to KeTMR. KeJuR shows a robust PA signal under 860 nm excitation and can be paired with traditional PA dyes for multiplex imaging in blood samples under a tissue-mimicking environment.

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JO - Chemical Communications

JF - Chemical Communications

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A long-wavelength xanthene dye for photoacoustic imaging

Abstract

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