Abstract
A method is described for measuring antibody-dependent cellular cytotoxicity (ADCC) of mononuclear cells from human peripheral blood using an established murine cell line and commercially prepared antisera. The test utilizes a standard 51Cr release technique. The ADCC activity of mononuclear cells obtained from 10 healthy human volunteers was measured at 4 different effector: target cell ratios. A linear relationship between %51Cr release (ADCC) and the number of effector cells was observed.
Original language | English (US) |
---|---|
Pages (from-to) | 277-282 |
Number of pages | 6 |
Journal | Journal of Immunological Methods |
Volume | 79 |
Issue number | 2 |
DOIs | |
State | Published - May 23 1985 |
Keywords
- antibody-dependent cellular cytotoxicity
- cell-mediated cytotoxicity
- human mononuclear cells
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology