TY - GEN
T1 - A molecular communication system model based on biological circuits
AU - Pierobon, Massimiliano
PY - 2014
Y1 - 2014
N2 - Molecular Communication (MC), i.e., the exchange of information through the emission, propagation, and reception of molecules, is a promising paradigm for the interconnection of autonomous nanoscale devices, known as nanomachines. Synthetic biology techniques, and in particular the engineering of biological circuits, are enabling research towards the programming of functions within biological cells, thus paving the way for the realization of biological nanomachines. The design of MC systems built upon biological circuits is particularly interesting since cells naturally employ the MC paradigm in their interactions, and possess many of the elements required to realize this type of communication. This paper focuses on the identification and systems-theoretic modeling of a minimal subset of biological circuit elements necessary to be included in an MC system design where the message-bearing molecules are propagated via free di?usion between two cells. The system-theoretic models are here detailed in terms of transfer functions, from which analytical expressions are derived for the attenuation and the delay experienced by an information signal through the MC system. Numerical results are presented to evaluate the attenuation and delay expressions as functions of realistic biological parameters.
AB - Molecular Communication (MC), i.e., the exchange of information through the emission, propagation, and reception of molecules, is a promising paradigm for the interconnection of autonomous nanoscale devices, known as nanomachines. Synthetic biology techniques, and in particular the engineering of biological circuits, are enabling research towards the programming of functions within biological cells, thus paving the way for the realization of biological nanomachines. The design of MC systems built upon biological circuits is particularly interesting since cells naturally employ the MC paradigm in their interactions, and possess many of the elements required to realize this type of communication. This paper focuses on the identification and systems-theoretic modeling of a minimal subset of biological circuit elements necessary to be included in an MC system design where the message-bearing molecules are propagated via free di?usion between two cells. The system-theoretic models are here detailed in terms of transfer functions, from which analytical expressions are derived for the attenuation and the delay experienced by an information signal through the MC system. Numerical results are presented to evaluate the attenuation and delay expressions as functions of realistic biological parameters.
KW - Molecular communication
KW - Nanonetworks
KW - Synthetic biology
UR - http://www.scopus.com/inward/record.url?scp=84905671636&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84905671636&partnerID=8YFLogxK
U2 - 10.1145/2619955.2619958
DO - 10.1145/2619955.2619958
M3 - Conference contribution
AN - SCOPUS:84905671636
SN - 1595930361
SN - 9781595930361
T3 - Proceedings of the 1st ACM International Conference on Nanoscale Computing and Communication, NANOCOM 2014
BT - Proceedings of the 1st ACM International Conference on Nanoscale Computing and Communication, NANOCOM 2014
PB - Association for Computing Machinery
T2 - 1st ACM International Conference on Nanoscale Computing and Communication, NANOCOM 2014
Y2 - 13 May 2014 through 14 May 2014
ER -