Abstract
The incidence of non-Hodgkin's lymphomas continues to rise and the number of deaths attributable to these malignancies currently rank in the top five causes of cancer-related deaths in the United States. Recent insights into the pathogenesis and molecular characterization of these disorders have led to improvements in a clinicopathologically relevant classification system, as well as in the ability to accurately diagnose specific entities. Several new treatment modalities have been developed which may improve the outcome for selected patients. A better understanding of the biology of non- Hodgkin's lymphomas will hopefully translate into different therapies with improved outcomes. This article describes a new system for classifying the non-Hodgkin's lymphomas, highlights key aspects of the pathogenesis of non- Hodgkin's lymphomas and briefly reviews clinical and therapeutic approaches to the most common of these lymphomas.
Original language | English (US) |
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Pages (from-to) | 197-208 |
Number of pages | 12 |
Journal | Internal Medicine |
Volume | 39 |
Issue number | 3 |
DOIs | |
State | Published - Mar 2000 |
Keywords
- Classification
- Pathogenesis
- Review
- Treatment
ASJC Scopus subject areas
- Internal Medicine