9 Scopus citations

Abstract

The incidence of non-Hodgkin's lymphomas continues to rise and the number of deaths attributable to these malignancies currently rank in the top five causes of cancer-related deaths in the United States. Recent insights into the pathogenesis and molecular characterization of these disorders have led to improvements in a clinicopathologically relevant classification system, as well as in the ability to accurately diagnose specific entities. Several new treatment modalities have been developed which may improve the outcome for selected patients. A better understanding of the biology of non- Hodgkin's lymphomas will hopefully translate into different therapies with improved outcomes. This article describes a new system for classifying the non-Hodgkin's lymphomas, highlights key aspects of the pathogenesis of non- Hodgkin's lymphomas and briefly reviews clinical and therapeutic approaches to the most common of these lymphomas.

Original languageEnglish (US)
Pages (from-to)197-208
Number of pages12
JournalInternal Medicine
Volume39
Issue number3
DOIs
StatePublished - Mar 2000

Keywords

  • Classification
  • Pathogenesis
  • Review
  • Treatment

ASJC Scopus subject areas

  • Internal Medicine

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