Abstract
A new statistical parametric model of carcinogenesis is proposed. The focus is on tumor latency times. The model makes use of extreme value theory following the line initially explored by Pike [1] and further developed by Klebanov et al. [2]. In this paper, we make the first attempt to take account of the interdependence between the cells in an initiated tissue developing into a malignant tumor. (C) 2000 Elsevier Science Ltd.
Original language | English (US) |
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Pages (from-to) | 251-256 |
Number of pages | 6 |
Journal | Mathematical and Computer Modelling |
Volume | 32 |
Issue number | 1-2 |
DOIs | |
State | Published - Jul 2000 |
Externally published | Yes |
Keywords
- CED systems
- Carcinogenesis
- Cell dependence
- Extreme value theory
- Survival times
- Tumor latency times
ASJC Scopus subject areas
- Modeling and Simulation
- Computer Science Applications