Keyphrases
Epigenetics
100%
Medulloblastoma
100%
Terminal Protein
100%
Histone Deacetylases
100%
Bromodomain
100%
Panobinostat
75%
Musashi-1
37%
OTX015
37%
Dual Inhibition
25%
Co-treatment
25%
Molecular Mechanism
12%
Quantitative PCR
12%
Western Blot Analysis
12%
Apoptosis
12%
Cell Growth
12%
Overexpression
12%
Protein Expression
12%
Tumor Growth
12%
Clinically Significant
12%
MRNA Expression
12%
Epigenetic Regulation
12%
RNA Sequencing (RNA-seq)
12%
Oncogene
12%
Histone Deacetylase Inhibitor (HDACi)
12%
Therapeutic Potential
12%
Novel Therapeutics
12%
Xenograft
12%
Current Therapies
12%
Poor Clinical Outcomes
12%
G2 Cell Cycle Arrest
12%
Mechanistic Investigation
12%
Global Gene Expression
12%
Gene Knockout
12%
MYC Oncogene
12%
Suppressed Growth
12%
MYC Expression
12%
Single-agent Therapy
12%
Xenografted Mice
12%
Epigenetic Pathways
12%
Epigenetic Regulators
12%
Top 50
12%
Oncogene Amplification
12%
Bromodomain-containing Protein 4 (BRD4)
12%
Epigenetic Deregulation
12%
Pharmacology, Toxicology and Pharmaceutical Science
Histone Deacetylase
100%
Medulloblastoma
100%
Panobinostat
75%
Birabresib
37%
Mouse
12%
Western Blot
12%
Tumor Growth
12%
Medicine and Dentistry
Birabresib
42%
G2 Phase Cell Cycle Checkpoint
14%
Immunology and Microbiology
Biochemistry, Genetics and Molecular Biology
Histone Deacetylases Inhibitor
16%