A novel t(4;22)(q31;q12) produces an EWSR1-SMARCA5 fusion in extraskeletal Ewing sarcoma/primitive neuroectodermal tumor

Biochemistry, Genetics and Molecular Biology

• Ewing Sarcoma 100%
• Exon 40%
• Chromatin Remodeling 40%
• FLI1 40%
• Fluorescence in Situ Hybridization 20%
• Chromosomal Translocation 20%
• Cytogenetics 20%
• Reverse Transcription Polymerase Chain Reaction 20%
• C-Terminus 20%
• Carcinogenesis 20%
• Multigene Family 20%
• Candidate Gene 20%
• Transcription Factors 20%
• Fusion Protein 20%
• Anchorage Independent Growth 20%
• Cell Transformation 20%
• Rapid Amplification of cDNA Ends 20%
• Bacterial Artificial Chromosome 20%
• Fusion Transcript 20%
• Agar 20%
• ETS Transcription Factor Family 20%

Keyphrases

• SMARCA5 100%
• EWSR1-ETS 20%
• N-domain 10%
• SnF2 10%
• EWSR1-FLI1 Fusion 10%
• Tumor Features 10%
• EAT-2 10%