A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Daniel P. Flaherty; Yuxiang Dong; Jonathan L. Vennerstrom

doi:10.1016/j.tetlet.2009.08.083

A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Daniel P. Flaherty, Yuxiang Dong, Jonathan L. Vennerstrom

Pharmaceutical Science

Research output: Contribution to journal › Article

8 Scopus citations

Abstract

An efficient and widely applicable one-pot synthesis of unsymmetrical (E,E)-bis-styrylbenzenes using successive Heck and Horner-Wadsworth-Emmons reactions is described.

Original language	English (US)
Pages (from-to)	6228-6230
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	46
DOIs	https://doi.org/10.1016/j.tetlet.2009.08.083
State	Published - Nov 18 2009

Keywords

Alzheimer's disease
Bis-styrylbenzenes
Heck reaction
Horner-Wadsworth-Emmons reaction

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Cite this

Flaherty, D. P., Dong, Y., & Vennerstrom, J. L. (2009). A one-pot synthesis of unsymmetrical bis-styrylbenzenes. Tetrahedron Letters, 50(46), 6228-6230. https://doi.org/10.1016/j.tetlet.2009.08.083

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Access to Document

10.1016/j.tetlet.2009.08.083