A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Daniel P. Flaherty; Yuxiang Dong; Jonathan L. Vennerstrom

doi:10.1016/j.tetlet.2009.08.083

A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Daniel P. Flaherty, Yuxiang Dong, Jonathan L. Vennerstrom

Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

An efficient and widely applicable one-pot synthesis of unsymmetrical (E,E)-bis-styrylbenzenes using successive Heck and Horner-Wadsworth-Emmons reactions is described.

Original language	English (US)
Pages (from-to)	6228-6230
Number of pages	3
Journal	Tetrahedron Letters
Volume	50
Issue number	46
DOIs	https://doi.org/10.1016/j.tetlet.2009.08.083
State	Published - Nov 18 2009

Keywords

Alzheimer's disease
Bis-styrylbenzenes
Heck reaction
Horner-Wadsworth-Emmons reaction

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2009.08.083

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title = "A one-pot synthesis of unsymmetrical bis-styrylbenzenes",

abstract = "An efficient and widely applicable one-pot synthesis of unsymmetrical (E,E)-bis-styrylbenzenes using successive Heck and Horner-Wadsworth-Emmons reactions is described.",

keywords = "Alzheimer's disease, Bis-styrylbenzenes, Heck reaction, Horner-Wadsworth-Emmons reaction",

author = "Flaherty, {Daniel P.} and Yuxiang Dong and Vennerstrom, {Jonathan L.}",

note = "Funding Information: We thank UNMC, an American Foundation for Pharmaceutical Education (AFPE) pre-doctoral fellowship, a Josiah Kirby Lilly, Sr. Memorial AFPE pre-doctoral fellowship and a Nancy and Ronald Reagan Alzheimer{\textquoteright}s Scholarship Award for financial support. ",

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doi = "10.1016/j.tetlet.2009.08.083",

language = "English (US)",

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T1 - A one-pot synthesis of unsymmetrical bis-styrylbenzenes

AU - Flaherty, Daniel P.

AU - Dong, Yuxiang

AU - Vennerstrom, Jonathan L.

N1 - Funding Information: We thank UNMC, an American Foundation for Pharmaceutical Education (AFPE) pre-doctoral fellowship, a Josiah Kirby Lilly, Sr. Memorial AFPE pre-doctoral fellowship and a Nancy and Ronald Reagan Alzheimer’s Scholarship Award for financial support.

PY - 2009/11/18

Y1 - 2009/11/18

N2 - An efficient and widely applicable one-pot synthesis of unsymmetrical (E,E)-bis-styrylbenzenes using successive Heck and Horner-Wadsworth-Emmons reactions is described.

AB - An efficient and widely applicable one-pot synthesis of unsymmetrical (E,E)-bis-styrylbenzenes using successive Heck and Horner-Wadsworth-Emmons reactions is described.

KW - Alzheimer's disease

KW - Bis-styrylbenzenes

KW - Heck reaction

KW - Horner-Wadsworth-Emmons reaction

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JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

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ER -

A one-pot synthesis of unsymmetrical bis-styrylbenzenes

Abstract

Keywords

ASJC Scopus subject areas

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