A pediatric infectious diseases perspective of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and novel coronavirus disease 2019 (COVID-19) in children

Andi L. Shane, Alice I. Sato, Carol Kao, Felice C. Adler-Shohet, Surabhi B. Vora, Jeffery J. Auletta, Sharon Nachman, Vanessa N. Raabe, Kengo Inagaki, Ibukunoluwa C. Akinboyo, Charles Woods, Abdulsalam O. Alsulami, Mundeep K. Kainth, Roberto Parulan Santos, Claudia M. Espinosa, Julianne E. Burns, Coleen K. Cunningham, Samuel R. Dominguez, Beatriz Larru Martinez, Frank ZhuJonathan Crews, Taito Kitano, Lisa Saiman, Karen Kotloff

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Understanding the role that children play in the clinical burden and propagation of severe acute respiratory syndrome coronavirus 2, responsible for coronavirus disease 2019 (COVID-19) infections, is emerging. While the severe manifestations and acute clinical burden of COVID-19 have largely spared children compared with adults, understanding the epidemiology, clinical presentation, diagnostics, management, and prevention opportunities and the social and behavioral impacts on child health is vital. Foremost is clarifying the contribution of asymptomatic and mild infections to transmission within the household and community and the clinical and epidemiologic significance of uncommon severe post-infectious complications. Here, we summarize the current knowledge, identify resources, and outline research opportunities. Pediatric infectious diseases clinicians have a unique opportunity to advocate for the inclusion of children in epidemiological, clinical, treatment, and prevention studies to optimize their care as well as to represent children in the development of guidance and policy during pandemic response.

Original languageEnglish (US)
Pages (from-to)596-608
Number of pages13
JournalJournal of the Pediatric Infectious Diseases Society
Volume9
Issue number5
DOIs
StatePublished - 2020

Keywords

  • COVID-19
  • Children
  • Novel coronavirus
  • Pediatrics
  • SARS-CoV-2

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Infectious Diseases

Fingerprint

Dive into the research topics of 'A pediatric infectious diseases perspective of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and novel coronavirus disease 2019 (COVID-19) in children'. Together they form a unique fingerprint.

Cite this