A practical approach to reporting treatment abandonment in pediatric chronic conditions

Meaghann S. Weaver, Ramandeep S. Arora, Scott C. Howard, Carmen E. Salaverria, Yen Lin Liu, Raul C. Ribeiro, Catherine G. Lam

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

Treatment abandonment, the failure to complete therapy that is required for definitive disease control, frequently causes treatment failure for pediatric patients in low- and middle-income countries with chronic conditions, particularly cancer. Other forms of incomplete treatment affecting children in all settings, such as nonadherence and loss to follow-up, are often confused with treatment abandonment. Unclear definitions of incomplete treatment dramatically affect reported outcomes. To facilitate disease-specific and cross-sector analyses, we outline a practical approach to categorize forms of incomplete treatment, present distinct semantic categories with case examples and provide an algorithm that could be tailored to disease- and context-specific needs. Pediatr Blood Cancer 2015;62:565-570.

Original languageEnglish (US)
Pages (from-to)565-570
Number of pages6
JournalPediatric Blood and Cancer
Volume62
Issue number4
DOIs
StatePublished - Apr 1 2015

Keywords

  • Adherence
  • Chronic disease
  • Loss to follow-up
  • Outcome evaluation
  • Treatment abandonment
  • Treatment failure

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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  • Cite this

    Weaver, M. S., Arora, R. S., Howard, S. C., Salaverria, C. E., Liu, Y. L., Ribeiro, R. C., & Lam, C. G. (2015). A practical approach to reporting treatment abandonment in pediatric chronic conditions. Pediatric Blood and Cancer, 62(4), 565-570. https://doi.org/10.1002/pbc.25403