A Proposal for Addiction and Infectious Diseases Specialist Collaboration to Improve Care for Patients With Opioid Use Disorder and Injection Drug Use-Associated Infective Endocarditis

Nicolas Cortes-Penfield, Kelly Cawcutt, Bryan T. Alexander, Va Kara M.Meyer Karre, Alëna A. Balasanova

Research output: Contribution to journalArticlepeer-review

Abstract

Patients with injection drug use-associated infective endocarditis and opioid use disorder often receive treatment for the infection that fails to address its underlying cause. People who inject drugs (PWID) and develop serious infections also face disparities in antibiotic management, particularly with regards to use of outpatient parenteral antimicrobial therapy (OPAT). We highlight literature on OPAT in PWID challenging the notion that PWID cannot be managed with OPAT. Given that OPAT use amongst PWID and non-PWID yields similar outcomes, we argue that a bias against OPAT use in PWID is unwarranted and may reflect stigma rather than data. We further note the proven value of comprehensive OUD treatment on endocarditis treatment outcomes, which also addresses the potential safety concerns of OPAT in PWID, and propose a treatment model in which Addiction and Infectious Disease specialists collaborate to integrate opioid use disorder treatment into injection drug use-associated infective endocarditis care.

Original languageEnglish (US)
Pages (from-to)392-395
Number of pages4
JournalJournal of Addiction Medicine
Volume16
Issue number4
DOIs
StatePublished - Jul 1 2022

Keywords

  • PICC
  • infective endocarditis
  • injection drug use
  • opioid use disorder
  • outpatient parenteral antimicrobial therapy

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology (medical)

Fingerprint

Dive into the research topics of 'A Proposal for Addiction and Infectious Diseases Specialist Collaboration to Improve Care for Patients With Opioid Use Disorder and Injection Drug Use-Associated Infective Endocarditis'. Together they form a unique fingerprint.

Cite this