A prospective study of catheter-related complications of intrathecal drug delivery systems

Kenneth A. Follett, Claus P. Naumann

Research output: Contribution to journalArticlepeer-review

97 Scopus citations


Intrathecal drug administration via implanted pump is an effective treatment for intractable pain and spasticity but can be compromised by catheter-related complications. To determine the etiology of catheter-related complications, we have conducted a multicenter, prospective study of the long-term performance of a one-piece catheter system. Data pertaining to catheter-related complications were collected at implant and at specified times during the follow-up period. Catheter implantation characteristics that might affect complications were assessed. Two hundred nine patients were studied at 22 participating centers, with 1764 cumulative patient-months of catheter experience. Forty-nine catheter system complications occurred in 37 patients (7 complications related to the catheter itself, and 42 complications related to the implantation procedure). The 9-month complication-free 'survival' rate was 78.9% overall (95.5% for the catheter itself). No specific catheter implantation characteristics were associated with the occurrence of complications. These data indicate that the incidence of complications for a one-piece catheter system is similar to that of commercially available two-piece systems, and highlight the need for careful surgical technique during implantation. Copyright (C) 2000 U.S. Cancer Pain Relief Committee.

Original languageEnglish (US)
Pages (from-to)209-215
Number of pages7
JournalJournal of Pain and Symptom Management
Issue number3
StatePublished - Mar 2000
Externally publishedYes


  • Analgesic
  • Baclofen
  • Intraspinal
  • Morphine
  • Pain
  • Spasticity

ASJC Scopus subject areas

  • Nursing(all)
  • Clinical Neurology
  • Anesthesiology and Pain Medicine


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