TY - GEN
T1 - A prototype for multiple whole genome alignment
AU - Deogun, J. S.
AU - Ma, Fangrui
AU - Yang, Jingyi
AU - Benson, A.
N1 - Funding Information:
This research was supported in part by NSF EPSCOR Grant No. EPS-0091900 and NSF Digital Government Grant No. EIA-0091530.
Publisher Copyright:
© 2003 IEEE.
PY - 2003
Y1 - 2003
N2 - In this paper, we briefly describe a prototype of the software system we have developed for multiple whole genome alignment. To develop our algorithm, we have to solve several problems including decomposition of genomes with a suffix tree, finding an LIS for multiple MUM sequences, and iterative pairwise multiple sequence alignment. This results in an overall linear time complexity for our algorithm for finding conserved regions; and between linear and quadratic time complexity for multiple whole genome alignment. One application is the problem of finding a maximum set of conserved regions in closely related microorganisms.
AB - In this paper, we briefly describe a prototype of the software system we have developed for multiple whole genome alignment. To develop our algorithm, we have to solve several problems including decomposition of genomes with a suffix tree, finding an LIS for multiple MUM sequences, and iterative pairwise multiple sequence alignment. This results in an overall linear time complexity for our algorithm for finding conserved regions; and between linear and quadratic time complexity for multiple whole genome alignment. One application is the problem of finding a maximum set of conserved regions in closely related microorganisms.
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U2 - 10.1109/HICSS.2003.1174803
DO - 10.1109/HICSS.2003.1174803
M3 - Conference contribution
AN - SCOPUS:84969506741
T3 - Proceedings of the 36th Annual Hawaii International Conference on System Sciences, HICSS 2003
BT - Proceedings of the 36th Annual Hawaii International Conference on System Sciences, HICSS 2003
A2 - Sprague, Ralph H.
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 36th Annual Hawaii International Conference on System Sciences, HICSS 2003
Y2 - 6 January 2003 through 9 January 2003
ER -