A rapid Hg 2+ sensor based on aza-15-crown-5 ether functionalized 1,8-naphthalimide

Chen Hou, Alysha M. Urbanec, Haishi Cao

Research output: Contribution to journalArticlepeer-review

32 Scopus citations


A new 1,8-naphthalimide derivative bearing an aza-15-crown-5 macrocycle (1) has been synthesized as a chemosensor for Hg 2+ by a two-step reaction. The sensor shows selectivity to Hg 2+ over 11 other metal cations in aqueous media. Upon addition of Hg 2+, the fluorescence emission of the sensor at 537 nm is significantly quenched along with 22 nm blue-shift that makes this compound a useful sensor for Hg 2+ measurement.

Original languageEnglish (US)
Pages (from-to)4903-4905
Number of pages3
JournalTetrahedron Letters
Issue number38
StatePublished - Sep 21 2011


  • 1,8-Naphthalimide
  • Fluorescent sensor
  • Hg
  • ICT

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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