A reagent for the efficient cleavage of N-benzoylhomoserine lactones: Access to α-(2-phenylseleno)ethyl amino acids

Michelle L. Pedersen; David B. Berkowitz

doi:10.1016/S0040-4039(00)60175-2

A reagent for the efficient cleavage of N-benzoylhomoserine lactones: Access to α-(2-phenylseleno)ethyl amino acids

Michelle L. Pedersen, David B. Berkowitz

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Upon heating diphenyl diselenide and sodium trimethoxyborohydride (1:2) in DMF to 60°C, a reagent is produced which efficiently cleaves α-substituted N-benzoylhomoserine lactones to the corresponding α-(2-phenylseleno)ethyl amino acids without competing lactone reduction.

Original language	English (US)
Pages (from-to)	7315-7318
Number of pages	4
Journal	Tetrahedron Letters
Volume	33
Issue number	48
DOIs	https://doi.org/10.1016/S0040-4039(00)60175-2
State	Published - Nov 24 1992

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/S0040-4039(00)60175-2

Cite this

@article{c1959b207d104e62b0e51d819216269d,

title = "A reagent for the efficient cleavage of N-benzoylhomoserine lactones: Access to α-(2-phenylseleno)ethyl amino acids",

abstract = "Upon heating diphenyl diselenide and sodium trimethoxyborohydride (1:2) in DMF to 60°C, a reagent is produced which efficiently cleaves α-substituted N-benzoylhomoserine lactones to the corresponding α-(2-phenylseleno)ethyl amino acids without competing lactone reduction.",

author = "Pedersen, {Michelle L.} and Berkowitz, {David B.}",

year = "1992",

month = nov,

day = "24",

doi = "10.1016/S0040-4039(00)60175-2",

language = "English (US)",

volume = "33",

pages = "7315--7318",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "48",

}

TY - JOUR

T1 - A reagent for the efficient cleavage of N-benzoylhomoserine lactones

T2 - Access to α-(2-phenylseleno)ethyl amino acids

AU - Pedersen, Michelle L.

AU - Berkowitz, David B.

PY - 1992/11/24

Y1 - 1992/11/24

N2 - Upon heating diphenyl diselenide and sodium trimethoxyborohydride (1:2) in DMF to 60°C, a reagent is produced which efficiently cleaves α-substituted N-benzoylhomoserine lactones to the corresponding α-(2-phenylseleno)ethyl amino acids without competing lactone reduction.

AB - Upon heating diphenyl diselenide and sodium trimethoxyborohydride (1:2) in DMF to 60°C, a reagent is produced which efficiently cleaves α-substituted N-benzoylhomoserine lactones to the corresponding α-(2-phenylseleno)ethyl amino acids without competing lactone reduction.

UR - http://www.scopus.com/inward/record.url?scp=0026482698&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026482698&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)60175-2

DO - 10.1016/S0040-4039(00)60175-2

M3 - Article

AN - SCOPUS:0026482698

VL - 33

SP - 7315

EP - 7318

JO - Tetrahedron Letters

JF - Tetrahedron Letters

SN - 0040-4039

IS - 48

ER -

A reagent for the efficient cleavage of N-benzoylhomoserine lactones: Access to α-(2-phenylseleno)ethyl amino acids

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this