A retrospective assessment of the incidence of respiratory depression after neuraxial morphine administration for postcesarean delivery analgesia

Theresa R. Crowgey, Jennifer E. Dominguez, Cathleen Peterson-Layne, Terrence K. Allen, Holly A. Muir, Ashraf S. Habib

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

Respiratory depression can occur after neuraxial morphine administration. In the obstetric population, there are little data on respiratory depression after neuraxial morphine administration in women undergoing cesarean delivery. In this single-center, retrospective study in 5036 obstetric patients (mean body mass index = 34 kg/m) who underwent cesarean delivery and received neuraxial morphine, we did not identify any instances of respiratory depression requiring naloxone administration or rapid response team involvement. Therefore, the upper 95% confidence limit for respiratory depression in our study is 0.07% (1 event per 1429 cases).

Original languageEnglish (US)
Pages (from-to)1368-1370
Number of pages3
JournalAnesthesia and analgesia
Volume117
Issue number6
DOIs
StatePublished - Dec 2013

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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