A simple correlation method has been developed to predict effective diffusivities of small molecules in heterogeneous materials such as immobilized cell systems. This correlation uses a single diffusivity measurement at one cell volume fraction to predict diffusivities for any other volume fraction of cells. The method has been applied to 20 sets of published diffusivity measurements in immobilized cell systems and accurately predicts effective diffusivities of molecules for the full range of cell fractions. It may also be used to predict effective diffusivities in heterogeneous materials in which the diffusivity of a molecule in each phase and the volume fraction of each phase are known.
- diffusivity measurement
- immobilized cells
ASJC Scopus subject areas
- Applied Microbiology and Biotechnology