A simple correlation for predicting effective diffusivities in immobilized cell systems

Mark R. Riley; Fernando J. Muzzio; Helen M. Buettner; Sebastian C. Reyes

doi:10.1002/bit.260490202

A simple correlation for predicting effective diffusivities in immobilized cell systems

Mark R. Riley, Fernando J. Muzzio, Helen M. Buettner, Sebastian C. Reyes

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

A simple correlation method has been developed to predict effective diffusivities of small molecules in heterogeneous materials such as immobilized cell systems. This correlation uses a single diffusivity measurement at one cell volume fraction to predict diffusivities for any other volume fraction of cells. The method has been applied to 20 sets of published diffusivity measurements in immobilized cell systems and accurately predicts effective diffusivities of molecules for the full range of cell fractions. It may also be used to predict effective diffusivities in heterogeneous materials in which the diffusivity of a molecule in each phase and the volume fraction of each phase are known.

Original language	English (US)
Pages (from-to)	223-227
Number of pages	5
Journal	Biotechnology and Bioengineering
Volume	49
Issue number	2
DOIs	https://doi.org/10.1002/bit.260490202
State	Published - Jan 20 1996
Externally published	Yes

Keywords

diffusivity measurement
immobilized cells

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1002/bit.260490202

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title = "A simple correlation for predicting effective diffusivities in immobilized cell systems",

abstract = "A simple correlation method has been developed to predict effective diffusivities of small molecules in heterogeneous materials such as immobilized cell systems. This correlation uses a single diffusivity measurement at one cell volume fraction to predict diffusivities for any other volume fraction of cells. The method has been applied to 20 sets of published diffusivity measurements in immobilized cell systems and accurately predicts effective diffusivities of molecules for the full range of cell fractions. It may also be used to predict effective diffusivities in heterogeneous materials in which the diffusivity of a molecule in each phase and the volume fraction of each phase are known.",

keywords = "diffusivity measurement, immobilized cells",

author = "Riley, {Mark R.} and Muzzio, {Fernando J.} and Buettner, {Helen M.} and Reyes, {Sebastian C.}",

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AU - Riley, Mark R.

AU - Muzzio, Fernando J.

AU - Buettner, Helen M.

AU - Reyes, Sebastian C.

PY - 1996/1/20

Y1 - 1996/1/20

N2 - A simple correlation method has been developed to predict effective diffusivities of small molecules in heterogeneous materials such as immobilized cell systems. This correlation uses a single diffusivity measurement at one cell volume fraction to predict diffusivities for any other volume fraction of cells. The method has been applied to 20 sets of published diffusivity measurements in immobilized cell systems and accurately predicts effective diffusivities of molecules for the full range of cell fractions. It may also be used to predict effective diffusivities in heterogeneous materials in which the diffusivity of a molecule in each phase and the volume fraction of each phase are known.

AB - A simple correlation method has been developed to predict effective diffusivities of small molecules in heterogeneous materials such as immobilized cell systems. This correlation uses a single diffusivity measurement at one cell volume fraction to predict diffusivities for any other volume fraction of cells. The method has been applied to 20 sets of published diffusivity measurements in immobilized cell systems and accurately predicts effective diffusivities of molecules for the full range of cell fractions. It may also be used to predict effective diffusivities in heterogeneous materials in which the diffusivity of a molecule in each phase and the volume fraction of each phase are known.

KW - diffusivity measurement

KW - immobilized cells

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IS - 2

ER -

A simple correlation for predicting effective diffusivities in immobilized cell systems

Abstract

Keywords

ASJC Scopus subject areas

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