A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

Mao Sheng Cheng, Rong Shi Li, George Kenyon

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.

Original languageEnglish (US)
Pages (from-to)851-854
Number of pages4
JournalChinese Chemical Letters
Volume11
Issue number10
StatePublished - Oct 1 2000

Keywords

  • Antimalarial
  • Chalcones
  • Solid phase synthesis

ASJC Scopus subject areas

  • Chemistry(all)

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