A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

Mao Sheng Cheng; Rong Shi Li; George Kenyon

A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

Mao Sheng Cheng, Rong Shi Li, George Kenyon

Research output: Contribution to journal › Article › peer-review

Abstract

In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.

Original language	English (US)
Pages (from-to)	851-854
Number of pages	4
Journal	Chinese Chemical Letters
Volume	11
Issue number	10
State	Published - Oct 2000
Externally published	Yes

Keywords

Antimalarial
Chalcones
Solid phase synthesis

ASJC Scopus subject areas

General Chemistry

Cite this

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title = "A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations",

abstract = "In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.",

keywords = "Antimalarial, Chalcones, Solid phase synthesis",

author = "Cheng, {Mao Sheng} and Li, {Rong Shi} and George Kenyon",

year = "2000",

month = oct,

language = "English (US)",

volume = "11",

pages = "851--854",

journal = "Chinese Chemical Letters",

issn = "1001-8417",

publisher = "Elsevier B.V.",

number = "10",

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TY - JOUR

T1 - A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

AU - Cheng, Mao Sheng

AU - Li, Rong Shi

AU - Kenyon, George

PY - 2000/10

Y1 - 2000/10

N2 - In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.

AB - In order to accelerate the development of relatively inexpensive antimalarials that are effective against chloroquine-resistant strains of Plasmodium falclparum, a methodology for the solid phase synthesis of chalcone (1, 3-diphenyl-2-propen-l-one) analogues in reasonably high yields has been developed.

KW - Antimalarial

KW - Chalcones

KW - Solid phase synthesis

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UR - http://www.scopus.com/inward/citedby.url?scp=0034374847&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034374847

SN - 1001-8417

VL - 11

SP - 851

EP - 854

JO - Chinese Chemical Letters

JF - Chinese Chemical Letters

IS - 10

ER -

A Solid Phase Synthesis of Chalcones by Claisen-Schmidt Condensations

Abstract

Keywords

ASJC Scopus subject areas

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