A trial of etomidate for rapid sequence intubation in the emergency department

Daniel C. Smith, Joseph M. Bergen, Howard Smithline, Ronald Kirschner

Research output: Contribution to journalArticlepeer-review

47 Scopus citations


A number of pharmacologic agents have been used for induction during rapid sequence intubation (RSI). Some of these agents may have adverse effects that can limit their use in certain clinical settings. This study was undertaken to determine the safety and utility of etomidate in patients with a range of underlying clinical conditions. Thirty-four patients underwent RSI in the emergency department (ED). Hemodynamic measurements and clinical assessments were recorded before and after intubation. The results suggest that etomidate is a safe and effective agent for use in a range of patients undergoing RSI in the ED.

Original languageEnglish (US)
Pages (from-to)13-16
Number of pages4
JournalJournal of Emergency Medicine
Issue number1
StatePublished - Jan 2000
Externally publishedYes


  • Airway
  • Etomidate
  • Induction agents
  • Intubation
  • Rapid sequence intubation

ASJC Scopus subject areas

  • Emergency Medicine

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