Abstract
We present a new method for the quantitative estimation of blood flow velocity, based on the use of the Radon transform. The specific application is for measurement of blood flow velocity in the retina. Our modified fundus camera uses illumination from a green LED and captures imagery with a high-speed CCD camera. The basic theory is presented, and typical results are shown for an in vitro flow model using blood in a capillary tube. Subsequently, representative results are shown for representative fundus imagery. This approach provides absolute velocity and flow direction along the vessel center-line or any lateral displacement therefrom. We also provide an error analysis allowing estimation of confidence intervals for the estimated velocity.
Original language | English (US) |
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Article number | 056014 |
Journal | Journal of Biomedical Optics |
Volume | 15 |
Issue number | 5 |
DOIs | |
State | Published - Sep 2010 |
Externally published | Yes |
Keywords
- Absolute blood velocity
- Flow
- Perfusion
- Radon transform
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Biomaterials
- Atomic and Molecular Physics, and Optics
- Biomedical Engineering