ACE I/D genotype, habitual physical activity, and blood pressure in children

Mark A. Sarzynski, Joey C. Eisenmann, Gregory J. Welk, Jared Tucker, Kim Glenn, Max Rothschild, Kate Heelan

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p <.05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.

Original languageEnglish (US)
Pages (from-to)301-313
Number of pages13
JournalPediatric Exercise Science
Volume22
Issue number2
DOIs
StatePublished - May 2010

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Orthopedics and Sports Medicine
  • Physical Therapy, Sports Therapy and Rehabilitation

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