ACE I/D genotype, habitual physical activity, and blood pressure in children

Mark A. Sarzynski; Joey C. Eisenmann; Gregory J. Welk; Jared Tucker; Kim Glenn; Max Rothschild; Kate Heelan

doi:10.1123/pes.22.2.301

ACE I/D genotype, habitual physical activity, and blood pressure in children

Mark A. Sarzynski, Joey C. Eisenmann, Gregory J. Welk, Jared Tucker, Kim Glenn, Max Rothschild, Kate Heelan

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p <.05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.

Original language	English (US)
Pages (from-to)	301-313
Number of pages	13
Journal	Pediatric Exercise Science
Volume	22
Issue number	2
DOIs	https://doi.org/10.1123/pes.22.2.301
State	Published - May 2010

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Orthopedics and Sports Medicine
Physical Therapy, Sports Therapy and Rehabilitation

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abstract = "The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p <.05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.",

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AU - Sarzynski, Mark A.

AU - Eisenmann, Joey C.

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AU - Tucker, Jared

AU - Glenn, Kim

AU - Rothschild, Max

AU - Heelan, Kate

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AB - The present study examined the association between the angiotensin converting enzyme (ACE) insertion/deletion (I/D) polymorphism, physical activity, and resting blood pressure (BP) in a sample of 132 children (48.4% female). Children attaining 60 min/day of moderate-to-vigorous physical activity (MVPA) possessed lower % body fat (29% vs 24%, p <.05). Resting BP did not significantly differ between genotypes. Furthermore, partial correlations between MVPA and BP were low and did not vary by ACE genotype. Thus, the ACE I/D genotype is not associated with BP and does not modify the relationship between physical activity and BP in this sample of children.

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ACE I/D genotype, habitual physical activity, and blood pressure in children

Abstract

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