Abstract
Acute generalized exanthematous pustulosis (AGEP) is a rare skin eruption most commonly caused by medications. It is characterized by fever and the acute eruption of non-follicular pustules overlying erythrodermic skin. Histopathology shows subcorneal pustules with a background of dermal edema and spongiosis, leukocytoclastic vasculitis, perivascular eosinophils, and focal necrosis of keratinocytes. Three cases of clindamycin induced AGEP have been reported in the literature. A case of AGEP due to clindamycin is reported in a patient with numerous other drug allergies and without history of psoriasis. Presentation and treatment of AGEP are reviewed.
| Original language | English (US) |
|---|---|
| Article number | 15 |
| Journal | Dermatology Online Journal |
| Volume | 14 |
| Issue number | 7 |
| State | Published - Jul 2008 |
| Externally published | Yes |
ASJC Scopus subject areas
- Dermatology