TY - JOUR
T1 - Acute leukemia
AU - Schumacher, Harold R.
AU - Alvares, Carmelita J.
AU - Blough, Ruthann I.
AU - Mazzella, Fermina
PY - 2002
Y1 - 2002
N2 - This article provides a review of the acute leukemias with updated basic and practical information. The main emphasis is on techniques used to arrive at the correct diagnosis. Although morphology and cytochemistry were the mainstays of diagnosis in the past, new developments in immunophenotyping, cytogenetics, molecular biology, and in vitro assays have improved the understanding of this disease dramatically and enable the identification of new entities with distinct clinicobiologic features.
AB - This article provides a review of the acute leukemias with updated basic and practical information. The main emphasis is on techniques used to arrive at the correct diagnosis. Although morphology and cytochemistry were the mainstays of diagnosis in the past, new developments in immunophenotyping, cytogenetics, molecular biology, and in vitro assays have improved the understanding of this disease dramatically and enable the identification of new entities with distinct clinicobiologic features.
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U2 - 10.1016/S0272-2712(03)00071-4
DO - 10.1016/S0272-2712(03)00071-4
M3 - Review article
C2 - 11933574
AN - SCOPUS:0036128616
SN - 0272-2712
VL - 22
SP - 153
EP - 192
JO - Clinics in Laboratory Medicine
JF - Clinics in Laboratory Medicine
IS - 1
ER -