Acute renal failure: Unusual complication of Epstein-Barr virus-induced infectious mononucleosis

Paul S. Lei; Amy Lowichik; Wain Allen; Teri Jo Mauch

doi:10.1086/317497

Acute renal failure: Unusual complication of Epstein-Barr virus-induced infectious mononucleosis

Paul S. Lei, Amy Lowichik, Wain Allen, Teri Jo Mauch

Research output: Contribution to journal › Article › peer-review

21 Scopus citations

Abstract

A 17-year-old boy with juvenile rheumatoid arthritis presented with jaundice, confusion, hemolytic anemia, thrombocytopenia, and acute renal failure secondary to titer-confirmed acute Epstein-Barr virus (EBV). Renal biopsy specimen revealed interstitial nephritis with an inflammatory infiltrate composed of cytotoxic/suppressor T cells, and interstitial mononuclear cell nuclei expressed EBV encoded RNA-1 (EBER-1) mRNA. Methylprednisolone treatment resulted in rapid improvement.

Original language	English (US)
Pages (from-to)	1519-1524
Number of pages	6
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume	31
Issue number	6
DOIs	https://doi.org/10.1086/317497
State	Published - Dec 2000
Externally published	Yes

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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title = "Acute renal failure: Unusual complication of Epstein-Barr virus-induced infectious mononucleosis",

abstract = "A 17-year-old boy with juvenile rheumatoid arthritis presented with jaundice, confusion, hemolytic anemia, thrombocytopenia, and acute renal failure secondary to titer-confirmed acute Epstein-Barr virus (EBV). Renal biopsy specimen revealed interstitial nephritis with an inflammatory infiltrate composed of cytotoxic/suppressor T cells, and interstitial mononuclear cell nuclei expressed EBV encoded RNA-1 (EBER-1) mRNA. Methylprednisolone treatment resulted in rapid improvement.",

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year = "2000",

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AU - Allen, Wain

AU - Mauch, Teri Jo

PY - 2000/12

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AB - A 17-year-old boy with juvenile rheumatoid arthritis presented with jaundice, confusion, hemolytic anemia, thrombocytopenia, and acute renal failure secondary to titer-confirmed acute Epstein-Barr virus (EBV). Renal biopsy specimen revealed interstitial nephritis with an inflammatory infiltrate composed of cytotoxic/suppressor T cells, and interstitial mononuclear cell nuclei expressed EBV encoded RNA-1 (EBER-1) mRNA. Methylprednisolone treatment resulted in rapid improvement.

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Acute renal failure: Unusual complication of Epstein-Barr virus-induced infectious mononucleosis

Abstract

ASJC Scopus subject areas

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