Acyclovir to Prevent Cytomegalovirus Infection in Renal-Graft Recipients

Jane E. Grundy, Paul D. Griffiths, Henry H. Balfour, Alejo Erice, Courtney Fletcher, David L. Dunn

Research output: Contribution to journalLetter

2 Scopus citations

Abstract

To the Editor: In a recent prophylactic trial, Balfour et al. (May 25 issue)1reported a significantly reduced incidence of cytomegalovirus excretion in blood and urine in renal-transplant recipients given high doses of acyclovir from the time of transplantation. Active cytomegalovirus infection was defined by the isolation of cytomegalovirus from cultured specimens from any site. The exact details of the procedure used for viral isolation were not given, but it can be assumed that this involved the appearance of cytopathic effect in inoculated cell cultures. Therein lies a problem, since the very specimens that are to be tested for the. . .

Original languageEnglish (US)
Pages (from-to)1268-1269
Number of pages2
JournalNew England Journal of Medicine
Volume321
Issue number18
DOIs
StatePublished - Nov 2 1989

ASJC Scopus subject areas

  • Medicine(all)

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