Adrenal insufficiency as a presenting manifestation of nonsmall cell lung cancer

Khalid Mohammad, Ruxana T. Sadikot

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


The adrenals are a common site of metastases for lung cancers; adrenal insufficiency, however, as a presenting feature of lung cancer, is extremely rare. We report a case of primary adrenal insufficiency secondary to metastases from adenocarcinoma of the lung. Our patient presented with hypotension, abdominal pain, and weight loss. CT scans showed a right upper lobe mass and bilateral adrenal masses. The frequent occurrence of constitutional symptoms, metabolic derangements, and cardiovascular compromise in patients with advanced cancer may lead to an underestimation of the true incidence of adrenal insufficiency in this population.

Original languageEnglish (US)
Pages (from-to)665-667
Number of pages3
JournalSouthern Medical Journal
Issue number6
StatePublished - Jun 2009
Externally publishedYes


  • Adrenal insufficiency
  • Lung cancer
  • Metastasis

ASJC Scopus subject areas

  • General Medicine


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