Advances and challenges in understanding endosomal sorting and fission

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Endosomes play crucial roles in the cell, serving as focal and ‘triage’ points for internalized lipids and receptors. As such, endosomes are a critical branching point that determines whether receptors are sorted for degradation or recycling. This Viewpoint aims to highlight recent advances in endosome research, including key endosomal functions such as sorting and fission. Moreover, the Viewpoint addresses key technical and conceptual challenges in studying endosomes.

Original languageEnglish (US)
Pages (from-to)4187-4195
Number of pages9
JournalFEBS Journal
Volume290
Issue number17
DOIs
StatePublished - Sep 2023

Keywords

  • EHD1
  • RAB
  • actin
  • early endosome
  • fission
  • late endosome
  • recycling endosome
  • sorting endosome
  • trafficking

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Cell Biology

Fingerprint

Dive into the research topics of 'Advances and challenges in understanding endosomal sorting and fission'. Together they form a unique fingerprint.

Cite this