Advances and challenges in understanding endosomal sorting and fission

Naava Naslavsky; Steve Caplan

doi:10.1111/febs.16687

Advances and challenges in understanding endosomal sorting and fission

Naava Naslavsky, Steve Caplan

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Endosomes play crucial roles in the cell, serving as focal and ‘triage’ points for internalized lipids and receptors. As such, endosomes are a critical branching point that determines whether receptors are sorted for degradation or recycling. This Viewpoint aims to highlight recent advances in endosome research, including key endosomal functions such as sorting and fission. Moreover, the Viewpoint addresses key technical and conceptual challenges in studying endosomes.

Original language	English (US)
Pages (from-to)	4187-4195
Number of pages	9
Journal	FEBS Journal
Volume	290
Issue number	17
DOIs	https://doi.org/10.1111/febs.16687
State	Published - Sep 2023

Keywords

EHD1
RAB
actin
early endosome
fission
late endosome
recycling endosome
sorting endosome
trafficking

ASJC Scopus subject areas

Biochemistry
Molecular Biology
Cell Biology

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10.1111/febs.16687

Cite this

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KW - recycling endosome

KW - sorting endosome

KW - trafficking

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Advances and challenges in understanding endosomal sorting and fission

Abstract

Keywords

ASJC Scopus subject areas

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