Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality

K. Goodkin; F. L. Wilkie; M. Concha; C. H. Hinkin; S. Symes; T. T. Baldewicz; D. Asthana; R. K. Fujimura; D. Lee; M. H. Van Zuilen; I. Khamis; P. Shapshak; C. Eisdorfer

doi:10.1016/S0895-4356(01)00445-0

Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality

K. Goodkin, F. L. Wilkie, M. Concha, C. H. Hinkin, S. Symes, T. T. Baldewicz, D. Asthana, R. K. Fujimura, D. Lee, M. H. Van Zuilen, I. Khamis, P. Shapshak, C. Eisdorfer

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105 Scopus citations

Abstract

Older individuals (>50 years of age) now comprise over 11% of patients with AIDS in the United States. This percentage is expected to continue to grow, due both to the improved longevity of patients prescribed highly active antiretroviral therapy (HAART) and to new infections among older individuals. This review focuses on the neuropsychiatric and neurological conditions that are most likely to be affected by advancing age-HIV-1-associated cognitive-motor disorder, peripheral neuropathy, progressive multifocal leukoencephalopathy, primary CNS lymphoma, and risk for cerebrovascular accident. Age associations with incidence of these disorders and with treatment foci are specified. Implications for future changes in management are discussed.

Original language	English (US)
Pages (from-to)	S35-S43
Journal	Journal of Clinical Epidemiology
Volume	54
Issue number	12 SUPPL. 1
DOIs	https://doi.org/10.1016/S0895-4356(01)00445-0
State	Published - 2001
Externally published	Yes

Keywords

Aging
HIV-1 associated morbidity
Mortality
Neuro-AIDS conditions

ASJC Scopus subject areas

Epidemiology

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10.1016/S0895-4356(01)00445-0

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Goodkin, K., Wilkie, F. L., Concha, M., Hinkin, C. H., Symes, S., Baldewicz, T. T., Asthana, D., Fujimura, R. K., Lee, D., Van Zuilen, M. H., Khamis, I., Shapshak, P., & Eisdorfer, C. (2001). Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality. Journal of Clinical Epidemiology, 54(12 SUPPL. 1), S35-S43. https://doi.org/10.1016/S0895-4356(01)00445-0

Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality. / Goodkin, K.; Wilkie, F. L.; Concha, M.; Hinkin, C. H.; Symes, S.; Baldewicz, T. T.; Asthana, D.; Fujimura, R. K.; Lee, D.; Van Zuilen, M. H.; Khamis, I.; Shapshak, P.; Eisdorfer, C.

In: Journal of Clinical Epidemiology, Vol. 54, No. 12 SUPPL. 1, 2001, p. S35-S43.

Research output: Contribution to journal › Article › peer-review

Goodkin, K, Wilkie, FL, Concha, M, Hinkin, CH, Symes, S, Baldewicz, TT, Asthana, D, Fujimura, RK, Lee, D, Van Zuilen, MH, Khamis, I, Shapshak, P & Eisdorfer, C 2001, 'Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality', Journal of Clinical Epidemiology, vol. 54, no. 12 SUPPL. 1, pp. S35-S43. https://doi.org/10.1016/S0895-4356(01)00445-0

Goodkin, K. ; Wilkie, F. L. ; Concha, M. ; Hinkin, C. H. ; Symes, S. ; Baldewicz, T. T. ; Asthana, D. ; Fujimura, R. K. ; Lee, D. ; Van Zuilen, M. H. ; Khamis, I. ; Shapshak, P. ; Eisdorfer, C. / Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality. In: Journal of Clinical Epidemiology. 2001 ; Vol. 54, No. 12 SUPPL. 1. pp. S35-S43.

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AB - Older individuals (>50 years of age) now comprise over 11% of patients with AIDS in the United States. This percentage is expected to continue to grow, due both to the improved longevity of patients prescribed highly active antiretroviral therapy (HAART) and to new infections among older individuals. This review focuses on the neuropsychiatric and neurological conditions that are most likely to be affected by advancing age-HIV-1-associated cognitive-motor disorder, peripheral neuropathy, progressive multifocal leukoencephalopathy, primary CNS lymphoma, and risk for cerebrovascular accident. Age associations with incidence of these disorders and with treatment foci are specified. Implications for future changes in management are discussed.

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Aging and neuro-AIDS conditions and the changing spectrum of HIV-1-associated morbidity and mortality

Abstract

Keywords

ASJC Scopus subject areas

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