Alcohol use disorder: A pre-existing condition for COVID-19?

Kristina L. Bailey; Derrick R. Samuelson; Todd A. Wyatt

doi:10.1016/j.alcohol.2020.10.003

Alcohol use disorder: A pre-existing condition for COVID-19?

Kristina L. Bailey, Derrick R. Samuelson, Todd A. Wyatt

Research output: Contribution to journal › Review article › peer-review

44 Scopus citations

Abstract

Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

Original language	English (US)
Pages (from-to)	11-17
Number of pages	7
Journal	Alcohol
Volume	90
DOIs	https://doi.org/10.1016/j.alcohol.2020.10.003
State	Published - Feb 2021

Keywords

COVID-19
SARS-CoV-2
alcohol
coronavirus
injury
lung

ASJC Scopus subject areas

Health(social science)
Biochemistry
Toxicology
Neurology
Behavioral Neuroscience

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10.1016/j.alcohol.2020.10.003

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title = "Alcohol use disorder: A pre-existing condition for COVID-19?",

abstract = "Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.",

keywords = "COVID-19, SARS-CoV-2, alcohol, coronavirus, injury, lung",

author = "Bailey, {Kristina L.} and Samuelson, {Derrick R.} and Wyatt, {Todd A.}",

note = "Publisher Copyright: {\textcopyright} 2020",

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month = feb,

doi = "10.1016/j.alcohol.2020.10.003",

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TY - JOUR

T1 - Alcohol use disorder

T2 - A pre-existing condition for COVID-19?

AU - Bailey, Kristina L.

AU - Samuelson, Derrick R.

AU - Wyatt, Todd A.

PY - 2021/2

Y1 - 2021/2

N2 - Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

AB - Alcohol misuse is long established as a contributor to the pathophysiology of the lung. The intersection of multi-organ responses to alcohol-mediated tissue injury likely contributes to the modulation of lung in response to injury. Indeed, the negative impact of alcohol on susceptibility to infection and on lung barrier function is now well documented. Thus, the alcohol lung represents a very likely comorbidity for the negative consequences of both COVID-19 susceptibility and severity. In this review, we present the known alcohol misuse ramifications on the lung in the context of the current coronavirus pandemic.

KW - COVID-19

KW - SARS-CoV-2

KW - alcohol

KW - coronavirus

KW - injury

KW - lung

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DO - 10.1016/j.alcohol.2020.10.003

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AN - SCOPUS:85095755901

SN - 0741-8329

VL - 90

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JO - Alcohol

JF - Alcohol

ER -

Alcohol use disorder: A pre-existing condition for COVID-19?

Abstract

Keywords

ASJC Scopus subject areas

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