Allergenicity of various peanut products as determined by RAST inhibition

Julie A. Nordlee, Steve L. Taylor, R. T. Jones, John W. Yunginger

Research output: Contribution to journalArticlepeer-review

100 Scopus citations

Abstract

Extracts of 19 different peanut products and peanut oil were tested for their allergenicity by the radioallergosorbent test inhibition assay using a crude peanut extract from raw peanuts as the standard for comparison. Seventeen of the extracts were able to competitively inhibit the binding of serum IgE from peanut-sensitive patients with the solid-phase raw peanut extract. Peanut oil and the extract from hydrolyzed peanut protein did not inhibit binding, which suggests that these products are not allergenic. The peanut hull flour extract showed a slight ability to inhibit binding, suggesting that this product contains minor amounts of the peanut allergen.

Original languageEnglish (US)
Pages (from-to)376-382
Number of pages7
JournalThe Journal of Allergy and Clinical Immunology
Volume68
Issue number5
DOIs
StatePublished - Nov 1981
Externally publishedYes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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