Abstract
We herein report an improved synthesis of 6-substituted-5H-pyrrolo[2,3-b] pyrazines utilizing microwave heating. The reaction is a palladium-catalyzed heteroannulation process followed by deprotection to yield the desired substrates in good yield.
Original language | English (US) |
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Pages (from-to) | 8631-8633 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 45 |
Issue number | 47 |
DOIs | |
State | Published - Nov 15 2004 |
Externally published | Yes |
Keywords
- 6-Substituted-5H-pyrrolo[2,3-b]pyrazine
- Cyclization
- Heteroannulation
- Microwave
- Palladium
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry