Abstract
Treatment of esters with diisobutylaluminum hydride (DIBAL) in the presence of lithio-trialkylphosphonoacetate results in improved yields of the homologated α, β-unsaturated esters. The problematic overreduction, which has previously observed in the half reduction of esters using DIBAL, is minimal (<3%) under these conditions.
Original language | English (US) |
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Pages (from-to) | 1257-1260 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 27 |
Issue number | 11 |
DOIs | |
State | Published - 1986 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry