An in Vivo Experimental Protocol for Identifying and Evaluating Dietary Factors That Delay Tumor Onset: Effect of Red Wine Solids

Consumption of fruit and vegetable rich diets is protective against cancer, however, the actual dietary factors that may be involved are not known. Recent epidemiologic evidence also indicates that wine may contain non-alcoholic constituents which protect against cancer. We describe a transgenic animal model combined with a chemically defined diet that can be used to identify foods, beverages, and/or their constituents that delay tumor onset in vivo.