TY - JOUR
T1 - An international collaborative standardizing a comprehensive patient-centered outcomes measurement set for colorectal cancer
AU - Colorectal Cancer Working Group of the International Consortium for Health Outcomes Measurement (ICHOM)
AU - Zerillo, Jessica A.
AU - Schouwenburg, Maartje G.
AU - Van Bommel, Annelotte C.M.
AU - Stowell, Caleb
AU - Lippa, Jacob
AU - Bauer, Donna
AU - Berger, Ann M.
AU - Boland, Gilles
AU - Borras, Josep M.
AU - Buss, Mary K.
AU - Cima, Robert
AU - Van Cutsem, Eric
AU - Van Duyn, Eino B.
AU - Finlayson, Samuel R.G.
AU - Cheng, Skye Hung Chun
AU - Langelotz, Corinna
AU - Lloyd, John
AU - Lynch, Andrew C.
AU - Mamon, Harvey J.
AU - McAllister, Pamela K.
AU - Minsky, Bruce D.
AU - Ngeow, Joanne
AU - Abu Hassan, Muhammad R.
AU - Ryan, Kim
AU - Shankaran, Veena
AU - Upton, Melissa P.
AU - Zalcberg, John
AU - Van De Velde, Cornelis J.
AU - Tollenaar, Rob
N1 - Publisher Copyright:
Copyright 2017 American Medical Association. All rights reserved.
PY - 2017/5/1
Y1 - 2017/5/1
N2 - IMPORTANCE: Global health systems are shifting toward value-based care in an effort to drive better outcomes in the setting of rising health care costs. This shift requires a common definition of value, starting with the outcomes that matter most to patients. OBJECTIVE: The International Consortium for Health Outcomes Measurement (ICHOM), a nonprofit initiative, was formed to define standard sets of outcomes by medical condition. In this article, we report the efforts of ICHOM's working group in colorectal cancer. EVIDENCE REVIEW: The working group was composed of multidisciplinary oncology specialists in medicine, surgery, radiation therapy, palliative care, nursing, and pathology, along with patient representatives. Through a modified Delphi process during 8 months (July 8, 2015 to February 29, 2016), ICHOM led the working group to a consensus on a final recommended standard set. The process was supported by a systematic PubMed literature review (1042 randomized clinical trials and guidelines from June 3, 2005, to June 3, 2015), a patient focus group (11 patients with early and metastatic colorectal cancer convened during a teleconference in August 2015), and a patient validation survey (among 276 patients with and survivors of colorectal cancer between October 15, 2015, and November 4, 2015). FINDINGS: After consolidating findings of the literature review and focus group meeting, a list of 40 outcomes was presented to the WG and underwent voting. The final recommendation includes outcomes in the following categories: survival and disease control, disutility of care, degree of health, and quality of death. Selected case-mix factors were recommended to be collected at baseline to facilitate comparison of results across treatments and health care professionals. CONCLUSIONS: A standardized set of patient-centered outcome measures to inform value-based health care in colorectal cancer was developed. Pilot efforts are under way to measure the standard set among members of the working group.
AB - IMPORTANCE: Global health systems are shifting toward value-based care in an effort to drive better outcomes in the setting of rising health care costs. This shift requires a common definition of value, starting with the outcomes that matter most to patients. OBJECTIVE: The International Consortium for Health Outcomes Measurement (ICHOM), a nonprofit initiative, was formed to define standard sets of outcomes by medical condition. In this article, we report the efforts of ICHOM's working group in colorectal cancer. EVIDENCE REVIEW: The working group was composed of multidisciplinary oncology specialists in medicine, surgery, radiation therapy, palliative care, nursing, and pathology, along with patient representatives. Through a modified Delphi process during 8 months (July 8, 2015 to February 29, 2016), ICHOM led the working group to a consensus on a final recommended standard set. The process was supported by a systematic PubMed literature review (1042 randomized clinical trials and guidelines from June 3, 2005, to June 3, 2015), a patient focus group (11 patients with early and metastatic colorectal cancer convened during a teleconference in August 2015), and a patient validation survey (among 276 patients with and survivors of colorectal cancer between October 15, 2015, and November 4, 2015). FINDINGS: After consolidating findings of the literature review and focus group meeting, a list of 40 outcomes was presented to the WG and underwent voting. The final recommendation includes outcomes in the following categories: survival and disease control, disutility of care, degree of health, and quality of death. Selected case-mix factors were recommended to be collected at baseline to facilitate comparison of results across treatments and health care professionals. CONCLUSIONS: A standardized set of patient-centered outcome measures to inform value-based health care in colorectal cancer was developed. Pilot efforts are under way to measure the standard set among members of the working group.
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U2 - 10.1001/jamaoncol.2017.0417
DO - 10.1001/jamaoncol.2017.0417
M3 - Review article
C2 - 28384684
AN - SCOPUS:85020082456
SN - 2374-2437
VL - 3
SP - 686
EP - 694
JO - JAMA Oncology
JF - JAMA Oncology
IS - 5
ER -