This clinical review of 70 polytetrafluoroethylene femoropopliteal and femoral-distal (tibial or peroneal) bypasses for limb salvage analyzes factors that influence graft patency. Patients with "good" angiographic run-off (n = 26) had a significantly better (P < 0.01) cumulative patency rate when compared to patients with "poor" (n = 43) angiographic run-off. Other factors which had a significant influence on graft patency over the 2-year follow-up included site of distal anastomosis (femoropopliteal versus femoral-distal), and previously failed femoropopliteal bypass. Patients with a preoperative ankle/brachial Doppler pressure index of less than 0.2 had a 67% occlusion rate during the first postoperative month. Thrombectomy and distal revisions (patch or jump graft) following graft occlusion did not significantly prolong graft patency.
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