Analysis of factors influencing patency of polytetrafluoroethylene prostheses for limb salvage

Richard A. Yeager, Robert W. Hobson, Thomas G. Lynch, Zafar Jamil, Bing C. Lee, Krishna Jain, Roger Keys

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


This clinical review of 70 polytetrafluoroethylene femoropopliteal and femoral-distal (tibial or peroneal) bypasses for limb salvage analyzes factors that influence graft patency. Patients with "good" angiographic run-off (n = 26) had a significantly better (P < 0.01) cumulative patency rate when compared to patients with "poor" (n = 43) angiographic run-off. Other factors which had a significant influence on graft patency over the 2-year follow-up included site of distal anastomosis (femoropopliteal versus femoral-distal), and previously failed femoropopliteal bypass. Patients with a preoperative ankle/brachial Doppler pressure index of less than 0.2 had a 67% occlusion rate during the first postoperative month. Thrombectomy and distal revisions (patch or jump graft) following graft occlusion did not significantly prolong graft patency.

Original languageEnglish (US)
Pages (from-to)499-506
Number of pages8
JournalJournal of Surgical Research
Issue number5
StatePublished - May 1982
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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