Abstract
Nuclear envelope peptides of the rat ventral prostate in the molecular weight region 18,400 to 19,400 show marked androgen dependence. After castration these peptides disappear. Re-administration of testosterone restores them. They were not extracted by 0.1 M NaCl or 5% HClO4 but were partially extracted by 0.35 M NaCl and 1% Triton. These peptides were not present in rat liver nuclear envelopes. As these androgen-dependent non-histone peptides have similar characteristics to androgen-dependent peptides identified in the prostate nucleus, we conclude that the nuclear peptides are at least partially localized to the nuclear envelope.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 469-474 |
| Number of pages | 6 |
| Journal | Biochemical and Biophysical Research Communications |
| Volume | 125 |
| Issue number | 2 |
| DOIs | |
| State | Published - Dec 14 1984 |
ASJC Scopus subject areas
- Biophysics
- Biochemistry
- Molecular Biology
- Cell Biology
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Venkatraman, J. T., Howell, G. M., & Lefebvre, Y. A. (1984). Androgen-dependent peptides of the rat ventral prostate nuclear envelope. Biochemical and Biophysical Research Communications, 125(2), 469-474. https://doi.org/10.1016/0006-291X(84)90564-3