Abstract
Direct oral anticoagulants are becoming more commonplace for the treatment of nonvalvular atrial fibrillation and deep vein thrombosis. Unfortunately, effective reversal agents are not widely available limiting options for neurosurgical intervention during active anticoagulation. We report a case series of 3 patients treated for aneurysmal subarachnoid hemorrhage while taking direct oral anticoagulants. All three underwent open surgical clipping after adequate time was allowed for drug metabolism. Decision-making must take into account timing of intervention, drug half-life, and currently available reversal agents.
Original language | English (US) |
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Pages (from-to) | 65-67 |
Number of pages | 3 |
Journal | Interdisciplinary Neurosurgery: Advanced Techniques and Case Management |
Volume | 11 |
DOIs | |
State | Published - Mar 2018 |
Keywords
- Aneurysmal subarachnoid hemorrhage
- Direct oral anticoagulant
- Prothrombin complex concentrate
ASJC Scopus subject areas
- Surgery
- Clinical Neurology