Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes

Liju Song; Mei Cao; Chong Chen; Panpan Qi; Ningzhe Li; Daoyan Wu; Jingshan Peng; Xuege Wang; Mao Zhang; Guoku Hu; Jian Zhao

doi:10.1080/14786419.2016.1244201

Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes

Liju Song, Mei Cao, Chong Chen, Panpan Qi, Ningzhe Li, Daoyan Wu, Jingshan Peng, Xuege Wang, Mao Zhang, Guoku Hu, Jian Zhao

Pharmacology & Experimental Neuroscience (PEN)

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.

Original language	English (US)
Pages (from-to)	1347-1350
Number of pages	4
Journal	Natural Product Research
Volume	31
Issue number	11
DOIs	https://doi.org/10.1080/14786419.2016.1244201
State	Published - 2017

Keywords

Pyrrosia petiolosa ethyl acetate extract (PPEAE)
Staphylococcus aureus
antibacterial activity
composition analysis

ASJC Scopus subject areas

Analytical Chemistry
Biochemistry
Plant Science
Organic Chemistry

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10.1080/14786419.2016.1244201

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title = "Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes",

abstract = "The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.",

keywords = "Pyrrosia petiolosa ethyl acetate extract (PPEAE), Staphylococcus aureus, antibacterial activity, composition analysis",

author = "Liju Song and Mei Cao and Chong Chen and Panpan Qi and Ningzhe Li and Daoyan Wu and Jingshan Peng and Xuege Wang and Mao Zhang and Guoku Hu and Jian Zhao",

note = "Funding Information: This work was supported by the National Natural Science Foundation of China [grant number 31270175]; the Program for New Century Excellent Talents in University [grant number NCET-13-0397]; and the Fundamental Research Funds for the Central Universities [grant number 2013SCU04B14]. Publisher Copyright: {\textcopyright} 2016 Informa UK Limited, trading as Taylor & Francis Group.",

year = "2017",

doi = "10.1080/14786419.2016.1244201",

language = "English (US)",

volume = "31",

pages = "1347--1350",

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AU - Song, Liju

AU - Cao, Mei

AU - Chen, Chong

AU - Qi, Panpan

AU - Li, Ningzhe

AU - Wu, Daoyan

AU - Peng, Jingshan

AU - Wang, Xuege

AU - Zhang, Mao

AU - Hu, Guoku

AU - Zhao, Jian

N1 - Funding Information: This work was supported by the National Natural Science Foundation of China [grant number 31270175]; the Program for New Century Excellent Talents in University [grant number NCET-13-0397]; and the Fundamental Research Funds for the Central Universities [grant number 2013SCU04B14]. Publisher Copyright: © 2016 Informa UK Limited, trading as Taylor & Francis Group.

PY - 2017

Y1 - 2017

N2 - The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.

AB - The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.

KW - Pyrrosia petiolosa ethyl acetate extract (PPEAE)

KW - Staphylococcus aureus

KW - antibacterial activity

KW - composition analysis

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Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes

Abstract

Keywords

ASJC Scopus subject areas

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