TY - JOUR
T1 - Antibacterial activity of Pyrrosia petiolosa ethyl acetate extract against Staphylococcus aureus by decreasing hla and sea virulence genes
AU - Song, Liju
AU - Cao, Mei
AU - Chen, Chong
AU - Qi, Panpan
AU - Li, Ningzhe
AU - Wu, Daoyan
AU - Peng, Jingshan
AU - Wang, Xuege
AU - Zhang, Mao
AU - Hu, Guoku
AU - Zhao, Jian
PY - 2017
Y1 - 2017
N2 - The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.
AB - The aim of this study was to explore the antibacterial activity of Pyrrosia petiolosa ethyl acetate extract (PPEAE) against Staphylococcus aureus in vitro and analyse its chemical components by gas chromatograph-mass spectrometry. The results of anti-microbial assay revealed that PPEAE had strong inhibitory activity against S.aureus, with MIC and MBC of 7.8 and 15.6 mg/mL, respectively. The transcriptional levels of hla and sea were reduced to 14.33 and 46.39% at the MIC compared to the control. Analysing test result exhibited that eugenol made a great contribution to antibacterial activity. This experiment indicated that PPEAE had prominent antibacterial activity against S. aureus.
KW - Pyrrosia petiolosa ethyl acetate extract (PPEAE)
KW - Staphylococcus aureus
KW - antibacterial activity
KW - composition analysis
UR - http://www.scopus.com/inward/record.url?scp=84992407815&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84992407815&partnerID=8YFLogxK
U2 - 10.1080/14786419.2016.1244201
DO - 10.1080/14786419.2016.1244201
M3 - Article
C2 - 27784177
AN - SCOPUS:84992407815
VL - 31
SP - 1347
EP - 1350
JO - Natural Product Research
JF - Natural Product Research
SN - 1478-6419
IS - 11
ER -