Application of the Sonogashira coupling reaction to the stereoselective synthesis of chiral 1,3-dienol ethers

Patrick H. Dussault, Darby G. Sloss, David J. Symonsbergen

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Sonogashira couplings of 2-iodo enol ethers or ynol ethers provide enynes which undergo semihydrogenation to afford 4-alkyl-1,3-dienol ethers. (1Z, 3E), (1E, 3Z) and (1Z, 3Z)-4-alkyl-1,3-dienol ethers are accessible using this strategy.

Original languageEnglish (US)
Pages (from-to)1387-1389
Number of pages3
JournalSynlett
Issue number12
DOIs
StatePublished - Dec 1998

ASJC Scopus subject areas

  • Organic Chemistry

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