Assay methods for cyclosporine monitoring following liver transplantation

Mary C. Haven; Linda M. Sobeski; Robert A. Earl; Rodney S. Markin

doi:10.1002/jcla.1860040214

Assay methods for cyclosporine monitoring following liver transplantation

Mary C. Haven, Linda M. Sobeski, Robert A. Earl, Rodney S. Markin

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

This article reviews therapeutic drug monitoring for cyclosporine in liver transplantation. Brief descriptions of various immunoassay methods include sample matrix selection, assay reagents, and metabolite cross‐reactivity information. Multiple comparisons of the various methods are outlined. Examples of the method‐dependent relationship between clinical events and changes in cyclosporine concentration are presented. Other potential predictors of liver allograft function are listed.

Original language	English (US)
Pages (from-to)	150-156
Number of pages	7
Journal	Journal of Clinical Laboratory Analysis
Volume	4
Issue number	2
DOIs	https://doi.org/10.1002/jcla.1860040214
State	Published - 1990

Keywords

Immunoassay
fluorescence polarization immunoassay

ASJC Scopus subject areas

Immunology and Allergy
Hematology
Public Health, Environmental and Occupational Health
Clinical Biochemistry
Medical Laboratory Technology
Biochemistry, medical
Microbiology (medical)

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10.1002/jcla.1860040214

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title = "Assay methods for cyclosporine monitoring following liver transplantation",

abstract = "This article reviews therapeutic drug monitoring for cyclosporine in liver transplantation. Brief descriptions of various immunoassay methods include sample matrix selection, assay reagents, and metabolite cross‐reactivity information. Multiple comparisons of the various methods are outlined. Examples of the method‐dependent relationship between clinical events and changes in cyclosporine concentration are presented. Other potential predictors of liver allograft function are listed.",

keywords = "Immunoassay, fluorescence polarization immunoassay",

author = "Haven, {Mary C.} and Sobeski, {Linda M.} and Earl, {Robert A.} and Markin, {Rodney S.}",

year = "1990",

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AU - Haven, Mary C.

AU - Sobeski, Linda M.

AU - Earl, Robert A.

AU - Markin, Rodney S.

PY - 1990

Y1 - 1990

N2 - This article reviews therapeutic drug monitoring for cyclosporine in liver transplantation. Brief descriptions of various immunoassay methods include sample matrix selection, assay reagents, and metabolite cross‐reactivity information. Multiple comparisons of the various methods are outlined. Examples of the method‐dependent relationship between clinical events and changes in cyclosporine concentration are presented. Other potential predictors of liver allograft function are listed.

AB - This article reviews therapeutic drug monitoring for cyclosporine in liver transplantation. Brief descriptions of various immunoassay methods include sample matrix selection, assay reagents, and metabolite cross‐reactivity information. Multiple comparisons of the various methods are outlined. Examples of the method‐dependent relationship between clinical events and changes in cyclosporine concentration are presented. Other potential predictors of liver allograft function are listed.

KW - Immunoassay

KW - fluorescence polarization immunoassay

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U2 - 10.1002/jcla.1860040214

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M3 - Review article

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ER -

Assay methods for cyclosporine monitoring following liver transplantation

Abstract

Keywords

ASJC Scopus subject areas

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