Assay methods for cyclosporine monitoring following liver transplantation

Mary C. Haven, Linda M. Sobeski, Robert A. Earl, Rodney S. Markin

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


This article reviews therapeutic drug monitoring for cyclosporine in liver transplantation. Brief descriptions of various immunoassay methods include sample matrix selection, assay reagents, and metabolite cross‐reactivity information. Multiple comparisons of the various methods are outlined. Examples of the method‐dependent relationship between clinical events and changes in cyclosporine concentration are presented. Other potential predictors of liver allograft function are listed.

Original languageEnglish (US)
Pages (from-to)150-156
Number of pages7
JournalJournal of Clinical Laboratory Analysis
Issue number2
StatePublished - 1990


  • Immunoassay
  • fluorescence polarization immunoassay

ASJC Scopus subject areas

  • Immunology and Allergy
  • Hematology
  • Public Health, Environmental and Occupational Health
  • Clinical Biochemistry
  • Medical Laboratory Technology
  • Biochemistry, medical
  • Microbiology (medical)


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