Association of facility type with overall survival in patients with nonsurgically managed pancreatic cancer

Josiah Mcallister, Saber Amin, Chi Lin

Research output: Contribution to journalArticlepeer-review

Abstract

Aim: To investigate the association between receiving treatment at academic centers and overall survival in pancreatic ductal adenocarcinoma patients who do not receive definitive surgery of the pancreatic tumor. Methods: Using the National Cancer Database, patients who were diagnosed with pancreatic ductal adenocarcinoma between 2004 to 2016 were identified. Results: Of 262,209 patients, 101,003 (38.5%) received treatment at academic centers. In the multivariable Cox regression analysis, patients who received treatment at a nonacademic facility had significantly worse overall survival compared with patients who were treated at an academic center (hazard ratio: 1.279; 95% CI: 1.268-1.290; p = 0.001). Conclusion: Compared with treatment at academic centers, treatment at nonacademic centers was associated with significantly worse overall survival in patients with nonsurgically managed pancreatic ductal adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)1273-1284
Number of pages12
JournalFuture Oncology
Volume18
Issue number10
DOIs
StatePublished - Mar 2022

Keywords

  • National Cancer Database
  • chemotherapy
  • facility type
  • overall survival
  • pancreatic adenocarcinoma
  • radiation therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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