Abstract
Aim: To investigate the association between receiving treatment at academic centers and overall survival in pancreatic ductal adenocarcinoma patients who do not receive definitive surgery of the pancreatic tumor. Methods: Using the National Cancer Database, patients who were diagnosed with pancreatic ductal adenocarcinoma between 2004 to 2016 were identified. Results: Of 262,209 patients, 101,003 (38.5%) received treatment at academic centers. In the multivariable Cox regression analysis, patients who received treatment at a nonacademic facility had significantly worse overall survival compared with patients who were treated at an academic center (hazard ratio: 1.279; 95% CI: 1.268-1.290; p = 0.001). Conclusion: Compared with treatment at academic centers, treatment at nonacademic centers was associated with significantly worse overall survival in patients with nonsurgically managed pancreatic ductal adenocarcinoma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1273-1284 |
| Number of pages | 12 |
| Journal | Future Oncology |
| Volume | 18 |
| Issue number | 10 |
| DOIs | |
| State | Published - Mar 2022 |
Keywords
- National Cancer Database
- chemotherapy
- facility type
- overall survival
- pancreatic adenocarcinoma
- radiation therapy
ASJC Scopus subject areas
- Oncology
- Cancer Research