TY - JOUR
T1 - Associations between Bioaerosol Exposures and Lung Function Changes among Dairy Workers in Colorado
AU - Martenies, Sheena E.
AU - Schaeffer, Joshua W.
AU - Erlandson, Grant
AU - Bradford, Mary
AU - Poole, Jill A.
AU - Wilson, Ander
AU - Weller, Zachary
AU - Reynolds, Stephen J.
AU - Magzamen, Sheryl
N1 - Funding Information:
Funding: This research was funded by grant number 1U01 OH010840 (MPI: Reynolds, Schaeffer, Magzamen) from the National Institute of Occupational Safety and Health and the Centers for Disease Control and Prevention. The study was also supported by grants from National Institute of Environmental Health Sciences (R01 ES019325l PI: Poole) and the National Institute of Occupational Safety and Health (U54 OH010162; PI: Rautiainen).
Publisher Copyright:
© 2020 The Author(s). Published by Wolters Kluwer Health, Inc.
PY - 2020/6/1
Y1 - 2020/6/1
N2 - Objective:Limited studies have examined effects of bioaerosols on the respiratory health of dairy workers; previous findings have been inconsistent across populations.Methods:Using a repeated measures design, exposures to dust, bioaerosols, and ozone were assessed and pre-and post-shift spirometry was performed for dairy workers (n=36). Workers completed 1 to 8 visits. Linear mixed effect models estimated associations between air pollutant constituents and changes in spirometry.Results:There was an association between higher dust exposures and increased peak expiratory flow rate. However, for all other outcomes there was no association with the exposures considered.Conclusions:Relationships between bioaerosol exposures and respiratory health in dairy workers remain unclear. Future studies should increase sample sizes, include repeated measures designs, vary the timing of spirometry measurements, and include markers for Gram positive bacteria such as muramic acid or peptidoglycan.
AB - Objective:Limited studies have examined effects of bioaerosols on the respiratory health of dairy workers; previous findings have been inconsistent across populations.Methods:Using a repeated measures design, exposures to dust, bioaerosols, and ozone were assessed and pre-and post-shift spirometry was performed for dairy workers (n=36). Workers completed 1 to 8 visits. Linear mixed effect models estimated associations between air pollutant constituents and changes in spirometry.Results:There was an association between higher dust exposures and increased peak expiratory flow rate. However, for all other outcomes there was no association with the exposures considered.Conclusions:Relationships between bioaerosol exposures and respiratory health in dairy workers remain unclear. Future studies should increase sample sizes, include repeated measures designs, vary the timing of spirometry measurements, and include markers for Gram positive bacteria such as muramic acid or peptidoglycan.
KW - bioaerosol
KW - dust
KW - ozone
KW - respiratory health
KW - spirometry
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U2 - 10.1097/JOM.0000000000001856
DO - 10.1097/JOM.0000000000001856
M3 - Article
C2 - 32221115
AN - SCOPUS:85086052537
SN - 1076-2752
VL - 62
SP - 427
EP - 430
JO - Journal of occupational and environmental medicine
JF - Journal of occupational and environmental medicine
IS - 6
ER -