Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands

James M. Takacs, D. Sahadeva Reddy, Shin A. Moteki, Di Wu, Hector Palencia

Research output: Contribution to journalArticle

150 Scopus citations

Abstract

A strategy is described for modular catalyst development based upon metal-directed self-assembly of bifunctional subunits around a structural metal to form a heteroleptic complex in which a second set of ligating groups are now suitably disposed to bind a second metal to form a catalytic site. A library of chiral diphosphites was prepared via metal-directed self-assembly and used in a simple asymmetric allylic amination, giving enantiomeric excesses as high as 97%.

Original languageEnglish (US)
Pages (from-to)4494-4495
Number of pages2
JournalJournal of the American Chemical Society
Volume126
Issue number14
DOIs
StatePublished - Apr 14 2004

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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