Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands

James M. Takacs; D. Sahadeva Reddy; Shin A. Moteki; Di Wu; Hector Palencia

doi:10.1021/ja049873+

Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands

James M. Takacs, D. Sahadeva Reddy, Shin A. Moteki, Di Wu, Hector Palencia

Research output: Contribution to journal › Article › peer-review

156 Scopus citations

Abstract

A strategy is described for modular catalyst development based upon metal-directed self-assembly of bifunctional subunits around a structural metal to form a heteroleptic complex in which a second set of ligating groups are now suitably disposed to bind a second metal to form a catalytic site. A library of chiral diphosphites was prepared via metal-directed self-assembly and used in a simple asymmetric allylic amination, giving enantiomeric excesses as high as 97%.

Original language	English (US)
Pages (from-to)	4494-4495
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	126
Issue number	14
DOIs	https://doi.org/10.1021/ja049873+
State	Published - Apr 14 2004

ASJC Scopus subject areas

Catalysis
General Chemistry
Biochemistry
Colloid and Surface Chemistry

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AU - Palencia, Hector

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Asymmetric Catalysis Using Self-Assembled Chiral Bidentate P,P-Ligands

Abstract

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